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(L51.2) Toxic epidermal necrolysis [lyell]
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258 583 in individuals diagnosis toxic epidermal necrolysis [lyell] confirmed
4 936 deaths with diagnosis toxic epidermal necrolysis [lyell]
2% mortality rate associated with the disease toxic epidermal necrolysis [lyell]
Diagnosis toxic epidermal necrolysis [lyell] is diagnosed Men are 2.26% more likely than Women
132 215
Men receive the diagnosis toxic epidermal necrolysis [lyell]
1 632 (1.2 %)Died from this diagnosis.
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126 368
Women receive the diagnosis toxic epidermal necrolysis [lyell]
3 304 (2.6 %)Died from this diagnosis.
Risk Group for the Disease toxic epidermal necrolysis [lyell] - Men and Women aged 0-5
In Men diagnosis is most often set at age 0-89
Less common in men the disease occurs at Age 90-95+in in women, the disease manifests at any age
In Women diagnosis is most often set at age 0-95+
Disease Features toxic epidermal necrolysis [lyell]
Absence or low individual and public risk
Toxic epidermal necrolysis [lyell] - what does this mean
Toxic epidermal necrolysis [lyell] is a rare and serious skin reaction that occurs when the body's immune system mistakenly attacks healthy skin cells. it is characterized by large areas of red, raised skin that form blisters and slough off, leaving raw and painful patches of skin. it can be caused by a reaction to a medication, infection, or other trigger.
What happens during the disease - toxic epidermal necrolysis [lyell]
Toxic epidermal necrolysis is a severe and potentially life-threatening skin disorder caused by an immune-mediated reaction to certain medications, infections, or other triggers. it is characterized by the rapid onset of widespread blistering and skin detachment, which can lead to systemic inflammation, sepsis, and organ failure. the exact pathogenesis of this disorder is not fully understood, but it is thought to involve a type iv hypersensitivity reaction, in which the immune system mistakenly attacks healthy cells. this leads to the release of inflammatory mediators, such as cytokines, which cause the skin to become inflamed and blister.
Clinical Pattern
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How does a doctor diagnose
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Treatment and Medical Assistance
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13 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Toxic epidermal necrolysis [lyell] - Prevention
Toxic epidermal necrolysis [lyell] can be prevented by avoiding exposure to certain medications, including some antibiotics, anticonvulsants, and non-steroidal anti-inflammatory drugs. it is also important to be aware of the signs and symptoms of this condition and seek medical help immediately if they develop. additionally, regular skin examinations and monitoring of medications can help prevent this condition.